New Computer for 6 x projectors

I'm looking for a strong computer and hardware setup which is capable of running 2 x 1080p projectors, 4 x 720p projectors and possibly an operator screen for running the show with Millumin.

Content likely on 1080 resolution on as many layers as posibble.

All frame syncked and hopefully on smooth 60fps. System also needs to be steady as it comes for a live event with long performance period.

What would you recommend?

Macmini with eGPU or/and Datapath? New MacPro? Something else?

Thank you for your responses!